首页|Hepatic Arterioportal Fistulas: A Retrospective Analysis of 97 Cases

Hepatic Arterioportal Fistulas: A Retrospective Analysis of 97 Cases

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Background and Aims: Hepatic arterioportal fistulas (HAPFs) are abnormal shunts or aberrant functional con-nections between the portal venous and the hepatic arte-rial systems. Detection of HAPFs has increased with the ad-vances in diagnostic techniques. Presence of HAPFs over a prolonged period can aggravate liver cirrhosis and further deteriorate liver function. However, the underlying causes of HAPFs and the treatment outcomes are now well character-ized. This study aimed to summarize the clinical character-istics of patients with HAPFs, and to compare the outcomes of different treatment modalities. Methods: Data of 97 pa-tients with HAPFs who were admitted to the Second Xiang-ya Hospital between January 2010 and January 2020 were retrospectively reviewed. Demographic information, clinical manifestations, underlying causes, treatment options, and short-term outcomes were analyzed. Results: The main cause of HAPF in our cohort was hepatocellular carcinoma (78/97, 80.41%), followed by cirrhosis (10/97, 10.31%). The main clinical manifestations were abdominal distention and abdominal pain. Treatment methods included transcath-eter arterial embolization (n=63, 64.9%), surgery (n=13, 13.4%), and liver transplantation (n=2, 2.1%); nineteen (19.6%) patients received conservative treatment. Among patients who underwent transcatheter arterial embolization, polyvinyl alcohol, lipiodol combined with gelatin sponge, and spring steel ring showed comparable efficacy. Conclusions:Hepatocellular carcinoma and cirrhosis are common causes of HAPFs. Transcatheter arterial embolization is a safe and effective method for the treatment of HAPFs, and polyvinyl alcohol, lipiodol combined with gelatin sponge, and spring steel ring showed comparable efficacy in our cohort.

Hepatic arterioportal fistulasEmbolizationHepatocellular carci-nomaCirrhosis.

Bendaxin Cao、Ke Tian、Hejun Zhou、Chenjie Li、Deliang Liu、Yuyong Tan

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Department of Respiratory and Critical Care Medicine,Affiliated Nanhua Hospital,University of South China,Hengyang,Hu-nan,China

Department of Gastroenterology,The Second Xiangya Hospital of Central South University,Changsha,Hunan,China

Research Center of Digestive Disease,Central South University,Changsha,Hunan,China

2022

临床与转化肝病杂志(英文版)

临床与转化肝病杂志(英文版)

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年,卷(期):2022.10(4)
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