首页|Hepatic Arterioportal Fistulas: A Retrospective Analysis of 97 Cases
Hepatic Arterioportal Fistulas: A Retrospective Analysis of 97 Cases
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Background and Aims: Hepatic arterioportal fistulas (HAPFs) are abnormal shunts or aberrant functional con-nections between the portal venous and the hepatic arte-rial systems. Detection of HAPFs has increased with the ad-vances in diagnostic techniques. Presence of HAPFs over a prolonged period can aggravate liver cirrhosis and further deteriorate liver function. However, the underlying causes of HAPFs and the treatment outcomes are now well character-ized. This study aimed to summarize the clinical character-istics of patients with HAPFs, and to compare the outcomes of different treatment modalities. Methods: Data of 97 pa-tients with HAPFs who were admitted to the Second Xiang-ya Hospital between January 2010 and January 2020 were retrospectively reviewed. Demographic information, clinical manifestations, underlying causes, treatment options, and short-term outcomes were analyzed. Results: The main cause of HAPF in our cohort was hepatocellular carcinoma (78/97, 80.41%), followed by cirrhosis (10/97, 10.31%). The main clinical manifestations were abdominal distention and abdominal pain. Treatment methods included transcath-eter arterial embolization (n=63, 64.9%), surgery (n=13, 13.4%), and liver transplantation (n=2, 2.1%); nineteen (19.6%) patients received conservative treatment. Among patients who underwent transcatheter arterial embolization, polyvinyl alcohol, lipiodol combined with gelatin sponge, and spring steel ring showed comparable efficacy. Conclusions:Hepatocellular carcinoma and cirrhosis are common causes of HAPFs. Transcatheter arterial embolization is a safe and effective method for the treatment of HAPFs, and polyvinyl alcohol, lipiodol combined with gelatin sponge, and spring steel ring showed comparable efficacy in our cohort.