首页|Current Evidence Concerning Effects of Ketogenic Diet and Intermittent Fasting in Patients with Nonalcoholic Fatty Liver

Current Evidence Concerning Effects of Ketogenic Diet and Intermittent Fasting in Patients with Nonalcoholic Fatty Liver

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Nonalcoholic fatty liver disease (NAFLD) is emerging glob-ally, while no therapeutic medication has been approved as an effective treatment to date, lifestyle intervention through dietary modification and physical exercise plays a critical role in NAFLD management. In terms of dietary modifica-tion, Mediterranean diet is the most studied dietary pattern and is recommended in many guidelines, however, it may not be feasible and affordable for many patients. Recently, a ketogenic diet and intermittent fasting have gained public at-tention and have been studied in the role of weight manage-ment. This article reviews specifically whether these trendy dietary patterns have an effect on NAFLD outcomes regard-ing intrahepatic fat content, fibrosis, and liver enzymes, the scientific rationales behind these particular dietary patterns, as well as the safety concerns in some certain patient groups.

Nonalcoholic fatty liver diseaseKetogenic diet, Intermittent fast-ingLifestyle modificationWeight reduction.

Pimsiri Sripongpun、Chaitong Churuangsuk、Chalermrat Bunchorntavakul

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Gastroenterology and Hepatology Unit,Division of Internal Medicine,Faculty of Medicine,Prince of Songkla University,Hat Yai,Thailand

Nutrition and Obesity Management Unit,Division of Internal Medicine,Faculty of Medicine,Prince of Songkla University,Hat Yai,Thailand

Division of Gastroenterology and Hepatology,Department of Medicine,Rajavithi Hospital,Rangsit University,Bangkok,Thailand

2022

10.14218/JCTH.2021.00494

临床与转化肝病杂志(英文版)

临床与转化肝病杂志(英文版)

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年,卷(期)：2022.10(4)
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