首页|Prospect of Animal Models for Acute-on-chronic Liver Failure: A Mini-review

Prospect of Animal Models for Acute-on-chronic Liver Failure: A Mini-review

扫码查看
Acute-on-chronic liver failure (ACLF) is a clinical syndrome that develops in patients with chronic liver diseases following a precipitating event and associated with a high mortality rate due to systemic multiorgan failure. Establishing a suita- ble and stable animal model to precisely elucidate the molec- ular basis of ACLF pathogenesis is essential for the develop- ment of effective early diagnostic and treatment strategies. In this context, this article provides a concise and inclusive review of breakthroughs in ACLF animal model development.

Liver failureAcute-on-chronic liver failureAnimal modelHepa-totoxicantsInflammation

Hozeifa Mohamed Hassan、Jun Li

展开 >

Precision Medicine Center,Taizhou Central Hospital(Taizhou University Hospital),Taizhou,Zhejiang,China

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Center for Infectious Diseases,National Medical Center for Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,Zhejiang,China

国家科技重大专项国家科技重大专项国家自然科学基金国家自然科学基金国家自然科学基金State's Key Project of Re-search and Development Plan of ChinaNational and Zhejiang Provincial special support program for high-level personnel recruitment(Ten-thou-sand Talents Program)

2017ZX103044022017ZX102032018183007381771196819019012016YFC1101303/4

2022

临床与转化肝病杂志(英文版)

临床与转化肝病杂志(英文版)

ISSN:
年,卷(期):2022.10(5)
  • 1
  • 5