首页|吲哚菁绿荧光腹腔镜技术在直肠癌手术中的应用价值分析

吲哚菁绿荧光腹腔镜技术在直肠癌手术中的应用价值分析

Analysis of the application value of indocyanine green fluorescence laparoscopic technique in rectal cancer surgery

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目的 探讨吲哚菁绿荧光腹腔镜技术在直肠癌手术中的应用价值.方法 前瞻性选取2021年3月至2023年11月于开封一五五医院行腹腔镜直肠癌根治术的直肠癌患者80例作为研究对象,依据是否应用吲哚菁绿荧光腹腔镜技术将入组患者随机分为研究组(吲哚菁绿荧光腹腔镜)和对照组(传统腹腔镜),每组各40例,比较两组患者的临床特征、手术及术后相关情况.结果 研究组和对照组在性别、体质量指数(BMI)、吸烟史、基础疾病史、美国麻醉医师协会(ASA)分级、肿瘤T分期、术后病理分期及肿瘤距肛缘距离方面进行比较,差异均无统计学意义(P>0.05).研究组术中出血量为(80.68±18.46)ml,低于对照组的(94.65±17.68)ml,差异有统计学意义(P=0.001).研究组患者术中吲哚菁绿荧光提示吻合口血运不佳、吻合不满意且术中吻合口重建4例,对照组术中无吻合口重建,两组比较差异有统计学意义(P=0.034).两组患者手术时间比较差异无统计学意义(P>0.05).研究组术中淋巴结清扫数目高于对照组[(18.43±3.59)枚vs.(14.02±3.10))枚,P<0.001],但两组的阳性淋巴结数目比较差异无统计学意义(P>0.05).两组患者术后首次下床时间、首次排气时间、首次进食时间及术后住院时间比较,差异均无统计学意义(P>0.05).两组患者术后并发症总发生率比较,差异无统计学意义(P>0.05),但对照组吻合口瘘的发生率显著高于研究组,差异有统计学意义(P=0.034).结论 吲哚菁绿荧光腹腔镜技术应用于直肠癌手术,可提高淋巴结清扫精度,还可实时评估吻合口吻合满意度、降低吻合口瘘的发生率.
Objective To investigate the application value of indocyanine green fluorescent laparoscopic technique in rectal cancer surgery.Methods A prospective study was conducted on 80 patients with rectal cancer who underwent concurrent surgical treatment at Kaifeng 155 Hospital from March 2021 to November 2023.According to whether indocyanine green fluorescence laparoscopy was applied,the enrolled patients were randomly divided into the study group(indocyanine green fluorescence laparoscopy,40 cases)and the control group(traditional laparoscopy,40 cases).The clinical features,operative and postoperative data of the two groups were compared and analyzed.Results There was no statistically significant difference between the study group and the control group in terms of gender,body mass index(BMI),smoking history,history of underlying diseases,ASA grading,tumor T staging,postoperative pathological staging,and distance from the tumor to the anal margin(P>0.05).The intraoperative blood loss in the study group was(80.68±18.46)ml,which was less than(94.65±17.68)ml in the control group with significant difference(P=0.001).Indocyanine green fluorescence indicated poor blood flow and unsatisfactory anastomosis in the study group,4 cases were reconstructed during the operation,and no anastomosis was reconstructed during the operation in the control group,the difference between the two groups was statistically significant(P=0.034).There was no significant difference in operation time between the two groups(P>0.05).The number of lymph nodes in the study group was higher than that in the control group(18.43±3.59 vs.14.02±3.10,P<0.001),but there was no significant difference in the number of positive lymph nodes between the two groups(P>0.05).There were no significant differences in the first time of getting out of bed,the first time of exhaust gas,the first time of eating and the time of hospitalization between the two groups(P>0.05).There was no significant difference in the total incidence of postoperative complications between the two groups(P>0.05),but the incidence of anastomotic fistula in the control group was significantly higher than that in the study group,with statistical significance(P=0.034).Conclusion The application of indocyanine green fluorescence laparoscopic technique in rectal cancer surgery can improve the accuracy of lymph node dissection,evaluate the satisfaction of anastomosis in real time,and reduce the incidence of anastomotic fistula.

Rectal cancerIndocyanine green fluorescenceLaparoscopyLymph node dissectionAnastomotic fistula

李明、彭银杰、刘磊、马腾、李开春、李沅咛、蒋辉辉、杜晨光、侯俊清、郭长升

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475003 河南开封 开封一五五医院普通外科

450002 河南省中医院普通外科

直肠癌 吲哚菁绿荧光 腹腔镜 淋巴结清扫 吻合口瘘

河南省医学科技攻关计划联合共建项目开封市科技攻关计划项目

LHGJ202308002303136

2024

临床肿瘤学杂志
解放军第八一医院

临床肿瘤学杂志

CSTPCD
影响因子:1.583
ISSN:1009-0460
年,卷(期):2024.29(5)
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