首页|影响食管癌胸腔镜食管切除术后肺部并发症的因素

影响食管癌胸腔镜食管切除术后肺部并发症的因素

Factors influencing pulmonary complications after thoracoscopic esophagectomy for esophageal cancer

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目的 探讨食管癌胸腔镜食管切除术后肺部并发症(PPC)的危险因素.方法 回顾性收集 2019 年 1 月至2022 年 6 月期间接受胸腔镜食管切除术的 181 例食管癌患者的临床病历资料.记录患者术后PPC发生情况.采用多因素Logistic回归模型分析影响PPC发生的因素,并构建列线图.结果 术后 46 例患者发生PCC.PPC与年龄、ASA分级、吸烟史、COPD和术后谵妄均有关(P<0.05);与其他临床病理参数无关(P>0.05).多因素Logistic回归分析结果显示年龄>60 岁、ASA分级Ⅲ/Ⅳ级、COPD和术后谵妄是PPC发生风险的独立危险因素(P<0.05).构建列线图预测模型显示C指数为 0.67(95%CI:0.62~0.72).结论 术前COPD和术后谵妄是食管癌患者胸腔镜食管切除术PPC风险的独立危险因素,建议采取预防措施以降低食管癌患者食管切除术PPC的发生率.
Objective To investigate the risk factors of pulmonary complications(PPC)after thoracoscopic esophagectomy for esophageal cancer.Methods Clinical data of 181 patients with esophageal cancer who underwent thoracoscopic esophagectomy from January 2019 to June 2022 were retrospectively collected.The occurrence of postoperative PPC was recorded.Multivariate Logistic regression model was used to analyze the factors affecting the occurrence of PPC,and a nomogram was constructed.Results PCC occurred in 46 patients after operation.PPC was associated with age,ASA grading,smoking history,COPD and postoperative delirium(P<0.05).There was no correlation with other clinicopathological parameters(P>0.05).Multivariate Logistic regression analysis showed that age>60 years old,ASA gradeⅢ/Ⅳ,COPD and postoperative delirium were independent risk factors for PPC(P<0.05).The constructed nomogram prediction model showed that the C index was 0.67(95%CI:0.62-0.72).Conclusion Preoperative COPD and postoperative delirium are independent risk factors for PPC in patients with esophageal cancer undergoing thoracoscopic esophagectomy.It is recommended to take preventive measures to reduce the incidence of PPC in patients with esophageal cancer undergoing esophagectomy.

Esophageal cancerThoracoscopic esophagectomyPostoperative pulmonary complicationRisk factors

仲飞燕、周晶晶、陈海生、仲扬荣

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226600 江苏南通 海安市人民医院胸外科

食管癌 胸腔镜食管切除术 术后肺部并发症 危险因素

2024

临床肿瘤学杂志
解放军第八一医院

临床肿瘤学杂志

CSTPCD
影响因子:1.583
ISSN:1009-0460
年,卷(期):2024.29(6)
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