Pathological classification and clinical application of ampullary carcinoma
Objective The anatomy of the periampullary region is complex.The origin of tumors in this area can be determined both by macroscopic location of main lesions and through immunohistochemical analysis,such as intestinal type and pancreaticobiliary type.However,histopathological type is limited by factors like staining methods,positive thresholds,and subjective evaluation by pathologists.Although most literature suggests that ampullary cancer has relatively low malignancy compared to pancreatic cancer,the lack of consistency in subtype assessment hinders progress in clinical diagnosis and treatment,with limited relevant data available domestically.This article aims to provide more references for clinical treatment and postoperative judgment by summarizing recent domestic and foreign reports on methods and standards for pathological typing of ampullary cancer,as well as content related to individualized anti-tumor schemes and clinical applications based on these methods.
Ampullary carcinomaIntestinal typePancreatobiliary typeMixed typeHistopathological type
NETL
NSTL
万方数据
