The diagnostic value of ultrasound-guided fine needle aspiration cytology for benign and malignant thyroid nodules
Objective To identify benign and malignant thyroid nodules(TN)by ultrasound-guided fine needle aspiration cytology(US-G FNAC).Methods A total of 192 TN patients who were treated in Xi'an Ninth Hospital from January 2020 to October 2022 were collected.All patients underwent postoperative pathological examination,ultrasound examination and US-G FNAC.The gold standard was the postoperative pathological results.The consistency of the findings and nodule properties of ultrasonography and US-G FNAC were tested,and the diagnostic value of ultrasonography and US-G FNAC in malignant thyroid nodules was analyzed.Results The pathological results showed 55 malignant nodules and 137 benign nodules.The results of ultrasound examination showed that 35 cases of malignant nodules and 127 cases of benign nodules,10 cases of misdiagnosis and 20 cases of missed diagnosis.The results of ultrasonography were consistent with those of pathological examination(Kappa=0.596,P＜0.05).US-G FNAC examination results showed that 46 cases of malignant nodules and 131 cases of benign nodules,6 cases of misdiagnosis and 9 cases of missed diagnosis,respectively.There was good consistency between US-G FNAC and postoperative pathological examination(Kappa=0.806,P＜0.05).The sensitivity,negative predictive value and accuracy(83.64％,93.57％,92.19％)of US-G FNAC in the diagnosis of thyroid malignant nodules were higher than those of ultrasound(P＜0.05).Conclusion Compared with conventional ultrasound,US-G FNAC can obtain higher differential value for benign and malignant thyroid nodules and has higher clinical application value.
Thyroid nodulesBenign and malignantUltrasoundFine needle aspirationCytology examination
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