Objective:To optimize ultrasound-assisted ethanol extraction of the total flavonoids from hawthorn pomace and determine the antioxidant capacity of the total flavonoids.Method:Hawthorn pomace is used as the raw material,and the yield of total flavonoids from hawthorn pomace as indicator,single-factor experiments are applied to analyze the effects of solid-liquid ratio,extraction time,ethanol volume fraction,and ultrasonic power on the yield of total flavonoids.The response surface methodology is applied to optimize the extraction process of total flavonoids from hawthorn pomace.Result:The opti-mal extraction conditions for ultrasound-assisted ethanol extraction of total flavonoids from hawthorn pomace:with a sol-id-liquid ratio of 1∶16 g/mL,under 450 W ultrasonic power,using 70％ethanol for extraction over 120 minutes.Under these conditions,the yield of total flavonoids from hawthorn pomace can reach 62.79 mg/g.Conclusion:Optimization of ultrason-ic-assisted ethanol extraction of total flavonoids from hawthorn pomace by response surface methodology is reasonable and reliable,and the best optimization of extraction technology is obtained.The total flavonoids from hawthorn pomace have strong antioxidant capacity.
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