Application value of different reconstruction methods in 18 F-AV 1451 PET/MR
Objective To investigate the application value of different reconstruction methods in the reconstruction of 18F-AV 1451 PET/MR.Methods A total of 22 patients with Alzheimer's disease who underwent 18F-AV 1451 PET/MR From March 2021 to Au-gust 2022 in General Hospital of Northern Theater Command were selected as the study objects.The brain PET images were reconstruc-ted by ordered subset expectation maximization(OSEM),OSEM+time of flight(TOF),OSEM+point spread function(PSF)and OS-EM+TOF+PSF.The contrast,signal to noise ratio and standardized uptake value ratio(SUVr)of brain PET images reconstructed by four reconstruction methods were recorded and compared.Results Compared with OSEM,OSEM+TOF,OSEM+PSF,OSEM+TOF+PSF increased the contrast,signal to noise ratio and SUVr in frontal,parietal,temporal,occipital and cingulate regions,and the differences were statistically significant(P<0.05).Conclusion The application of TOF and PSF can improve the contrast and sig-nal-to-noise ratio of brain PET image,make SUVr more accurate,and the combined application of OSEM+TOF+PSF has better image quality.
PET/MRTime of flightPoint spread functionAlzheimer's diseaseImage reconstruction
NETL
NSTL
万方数据
