The predictive value of parameters in blood routine examination to the degree of brain injury and the risk of death in pa-tients with intracranial hemorrhage
Objective To investigate the clinical value of parameters in blood routine examination for patients with intracranial hemor-rhage(ICH).Methods A total of 80 ICH patients admitted to The Second Affiliated Hospital of the Naval Medical University/Second Military Medical University from January 2021 to December 2023 were selected as the study objects.Patients were divided into mild brain injury group[glasgow coma scale(GCS)≥13 pionts,n =49]and moderate to severe brain injury group(GCS≤12 pionts,n =31)according to GCS.According to original intracerebral hemorrhage scale(OICH),the patients were divided into a low risk of death group(OICH≤2 pionts,n =64)and a high risk of death group(OICH≥3 pionts,n =16).General data and laboratory results of patients with mild brain injury were collected and compared with those with moderate and severe brain injury,and those with low and high risk of death.Receiver operating characteristic curve(ROC)was used to analyze the ability of parameters in blood routine exami-nation to predict the injury degree and death risk of ICH patients.Results The proportion of coronary heart disease history in moder-ate to severe brain injury group was higher than that in mild brain injury group,the difference was statistically significant(P＜0.05).White blood cell(WBC),neutrophil(N),C-reactive protein(CRP),monocyte to lymphocyte ratio(MLR),neutrophil to lymphocyte ra-tio(NLR),platelet to lymphocyte ratio(PLR),systemic immuno-inflammatory index(SII)and systemic inflammatory response index(SIRI)were all high in patients with moderate to severe brain injury in mild brain injury group,lymphocyte(L)was lower than that in mild brain injury group,and the differences were statistically significant(P＜0.05).WBC,N,MLR,NLR,PLR,SII and SIRI in the high death risk group were higher than those in the low death risk group,and L was lower than those in the low death risk group,with statistical significance(P＜0.05).ROC curve results showed that MLR,PLR,SII and SIRI predicted ICH patients with injury degree and death risk in lower area under ROC curve than NLR,the differences were statistically significant(P＜0.05).Conclusion NLR is of great value in predicting the degree of brain injury and the risk of death in ICH patients.
Intracranial HemorrhageBlood routineNeutrophil to lymphocyte ratioDegree of brain injuryRisk of death
NETL
NSTL
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