Efficacy and safety of intracardiac echocardiography-guided"one-stop"procedures that combined radiofrequency catheter ablation and left atrial appendage closure in patients with atrial fibrillation in different genders
Objective To investigate the clinical characteristics,efficacy and safety of the"one-stop"surgery of radiofrequency abla-tion combined with left atrial appendage closure under the guidance of intracardiac echocardiography(ICE)in different genders.Methods A total of 283 patients with atrial fibrillation who underwent"one-stop"surgery under the guidance of ICE in General Hos-pital of Northern Theater Command from November 2020 to June 2023 were retrospectively analyzed,and were divided into male group(n=162)and female group(n=121)according to their gender.The clinical characteristics,perioperative complications and postopera-tive follow-up results of the two groups were compared.Results There were statistically significant differences in age,CHA2DS2-VASc score,HAS-BLED score,left atrial diameter,left ventricular ejection fraction,creatinine clearance rate,cholesterol and the pro-portion of paroxysmal atrial fibrillation,smoking history,and drinking history between two groups(P<0.05).The proportion of electro-cardioversion,radiofrequency ablation time,total operation time and total exposure dose in the male group were higher than those in the female group,and the differences were statistically significant(P<0.05).The left atrial appendage occlusion devices were successfully implanted in all patients,and all included patients used Watchman occlusion devices.The proportion of 33 millimeters Watchman oc-clader used in male group was higher than that in female group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of peri-device leak and device related thrombosis at 3 months after operation between the two groups(P>0.05).There was no statistical difference in the atrial fibrillation recurrence rate between the two groups(P>0.05).There was no statistical difference in long-term complications during the follow-up period(P>0.05).Conclusion Different genders have their own clinical characteristics,and there are no gender difference in the efficacy and safety of the"one-stop"surgery of radio-frequency ablation combined with left atrial appendage closure under the guidance of ICE.
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