Value of strain analysis of echocardiography in differentiating hypertensive-left ventricular hypertrophy from cardiac amyloidosis
Objective To investigate the value of strain analysis of echocardiography in differentiating hypertensive-left ventricular hy-pertrophy(H-LVH)from cardiac amyloidosis(CA).Methods A total of 45 patients with CA admitted to the First Affiliated Hospital of Naval Medical University from June 2021 to June 2023 were included in Group A.In addition,50 patients with H-LVH admitted to our hospital during the same period were included in group B.Traditional echocardiographic parameters were recorded and compared between the two groups[left atrial diameter(LAd),left atrial volume index(LAVI),left ventricular end diastolic diameter(LVEDD),interventricular septal thickness at diastole(IVS),left ventricular posterior wall thickness(LVPW),early diastole peak flow velocity/late diastolic peak flow velocity(E/A),early diastole peak flow velocity/early diastolic mitral annular velocity(E/e'),left ventricular ejection fraction(LVEF)].The echocardiographic strain parameters were recorded and compared between the two groups[global longi-tudinal strain(GLS),left atrial reservoir strain(LASr),systolic strain rate(SRs),left atrial strain conduit phase(LAScd),early dias-tolic strain rate(SRe),left atrial strain contraction phase(LASct),late diastolic strain rate(SRa)].The differential diagnosis model was established by least absolute shrinkage and selection operator regression.Receiver operating characteristic(ROC)curve was drawn to evaluate the identification value of traditional parameter model and combined model for CA and H-LVH.Results IVS,LVPW,E/A and E/e'in group A were higher than those in group B,with statistical significance(P<0.05).GLS,LASr,SRs,LASct and SRa in group A were lower than those in group B,and the differences were statistically significant(P<0.05).The area under ROC curve of traditional parameter model and combined model for identifying CA and H-LVH were 0.854 and 0.916,sensitivity were 0.788 and 0.818,and specificity were 0.946 and 0.958,respectively.Conclusion Combining the traditional parameters of echocardiography with strain parameters can improve the differential value of CA and H-LVH.
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