合并糖尿病经皮冠状动脉介入术后患者心肺运动试验相关指标特征分析
Characteristics of cardiopulmonary exercise test in patients with diabetes after percutaneous coronary intervention
张莉莉 1张伊 1王圣熠 1王艳霞 1张剑 1梁延春 1张权宇1
作者信息
- 1. 北部战区总医院 心血管内科,辽宁 沈阳 110016
- 折叠
摘要
目的 分析合并糖尿病的经皮冠状动脉介入术(PCI)后患者的心肺运动试验(CPET)相关指标的特征.方法 回顾性分析北部战区总医院自2016 年2 月至2021 年12 月收治的出院前完成CPET的 5 087 例PCI后患者的一般临床资料.根据是否合并糖尿病将患者分为非糖尿病组(n=3 721)和糖尿病组(n=1 366).对两组进行倾向性评分匹配,比较两组的人口学信息、既往病史、实验室检查结果及CPET相关指标等.结果 匹配后,与非糖尿病组比较,糖尿病组体质量指数、肾小球滤过率水平更高(P<0.05),峰值心率、峰值公斤摄氧量、峰值代谢当量、氧通气当量、运动中峰值舒张压及血清肌酐水平更低(P<0.05).结论 合并糖尿病的PCI后患者的心肺功能相对较差.
Abstract
Objective To analyze the characteristics of cardiopulmonary exercise test(CPET)in patients with diabetes mellitus after percutaneous coronary intervention(PCI).Methods The clinical data of 5 087 post-PCI patients who completed CPET before dis-charge were retrospectively analyzed from February 2016 to December 2021 in the General Hospital of Northern Theater Command.Pa-tients were divided into non-diabetic group(n=3 721)and diabetic group(n=1 366)according to whether they had diabetes or not.The two groups were matched with propensity scores,and the demographic information,past medical history,laboratory test results and CPET related indexes of the two groups were compared.Results After matching,compared with non-diabetic group,the body mass in-dex and glomerular filtration rate in diabetic group were higher(P<0.05),and the peak heart rate,peak kg oxygen uptake,peak meta-bolic equivalent,oxygen ventilation equivalent,peak diastolic blood pressure and serum creatinine level during exercise were lower(P<0.05).Conclusion The cardiopulmonary function of patients with diabetes after PCI is relatively poor.
关键词
冠状动脉疾病/经皮冠状动脉介入术/糖尿病/心肺运动试验Key words
Coronary artery disease/Percutaneous coronary intervention/Diabetes mellitus/Cardiopulmonary exercise test引用本文复制引用
基金项目
辽宁省科技计划(2022JH2/101500028)
出版年
2024
NETL
NSTL
万方数据