Effect of inflammatory diet and vigorous-leisure time physical activity on mortality of cardiovascular disease
Objective To investigate the effects of inflammatory diet and vigorous-leisure time physical activity(v-LTPA)on the mor-tality of cardiovascular disease(CVD).Methods A total of 16 068 eligible participants were selected from the National Health and Nutrition Examination Survey Database from 2007 to 2014.According to the inflammatory properties of diet and the adequacy of v-LT-PA,patients were divided into group A(pro-inflammatory diet+insufficient v-LTPA,n=10 411),group B(anti-inflammatory diet+in-sufficient v-LTPA,n=2 196),and group C(pro-inflammatory diet+v-LTPA sufficient,n=2 456)and group D(anti-inflammatory diet+v-LTPA adequate,n=1 005).Data were read using R software and baseline characteristics of the four groups were compared.Multivariate Cox proportional hazard regression model was used to evaluate the effects of different inflammatory diets and v-LTPA on CVD mortality.Results There were significant differences in age,body mass index,estimated glomerular filtration rat,race,education level,male,hypertension,diabetes,hyperlipidemia,smoking and drinking among 4 groups(P<0.05).Compared with the lifestyle of group A,the lifestyle of group B and group D could reduce the mortality of CVD,and the multivariate adjusted hazard ratios were 0.71(95%confidence interval 0.53 to 0.92,P=0.020)and 0.31(95%confidence interval 0.12 to 0.80,P=0.016),respectively.In group C,lifestyle had no significant effect on CVD mortality,and the multivariable adjusted hazard ratio was 0.60(95%confidence in-terval 0.32 to 1.13,P=0.114).Conclusion Anti-inflammatory diet and sufficient v-LTPA can reduce the risk of CVD death,and anti-inflammatory diet can partially offset the harm of insufficient v-LTPA on CVD death.
Inflammatory dietHigh intensity leisure time physical exerciseCardiovascular diseasesNational Health and Nutrition Examination Survey Database