Analysis of therapeutic effect of 125 I radioactive particle implantation on spinal metastases of non-small cell lung cancer
Objective To investigate the efficacy of 125 I radioactive particle implantation in the treatment of spinal metastases in non-small cell lung cancer(NSCLC).Methods A total of 60 NSCLC patients with spinal metastasis admitted to Liaoning Provincial Peo-ple's Hospital of China Medical University from July 2019 to July 2022 were selected as the study objects.Visual analog scale(VAS)scores were recorded and compared with Japanese orthopedic association(JOA)scores and epidural spinal cord compression(ESCC)grades at one week before treatment and one,three and six months after treatment,respectively.Results One month after treatment,three months after treatment and six months after treatment,the VAS scores of patients were lower than those of one week before treat-ment,with statistical significance(P<0.05).The JOA scores of patients one month after treatment,three months after treatment and six months after treatment were all higher than those of one week before treatment,with statistical significance(P<0.05).The propor-tion of patients with ESCC grade three at six months after treatment was lower than that at one week before treatment,and the difference was statistically significant(P<0.05).Conclusion 125 I radioactive seed implantation in the treatment of NSCLC spinal metastases is safe and effective,which can not only significantly improve the quality of life of patients,but also play a positive role in the control of local spinal metastases.
Particle implantationNon-small cell lung cancerSpinal metastasisQuality of lifePain
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