Analysis of influencing factors of synchronous gastric cancer and metachronous gastric cancer after endoscopic submucosal dissection in patients with early gastric cancer
Objective To analyze the influencing factors of synchronous gastric cancer(SGC)and metachronous gastric cancer(MGC)in patients with early gastric cancer after endoscopic submucosal dissection(ESD).Methods The clinical data of 1 019 pa-tients with early gastric cancer admitted to Beijing Friendship Hospital of Capital Medical University from January 2017 to December 2023 were retrospectively analyzed.Patients were divided into single lesion group(no SGC or MGC)and multiple lesion group(SGC or MGC)according to the presence or absence of SGC or MGC.The clinical data and pathological characteristics of the two groups of pa-tients were collected.Logistic regression model was used to analyze the influencing factors of SGC and MGC after ESD in patients with early gastric cancer.Results Among the 1 019 patients,7 cases of SGC and 45 cases of MGC were found.There were statistically sig-nificant differences in age,smoking history,initial multiple lesions,initial lesion site,background mucosal atrophy degree,depth of tumor invasion,background mucosal enterification degree,and postoperative eCura grade between the two groups(P<0.05).Initial le-sion location in the lower part of the stomach,severe enterification,initial multiple lesions,and postoperative eCura grade C were inde-pendent risk factors for SGC and MGC after ESD in patients with early gastric cancer(P<0.05).Conclusion Early gastric cancer patients with initial lesion location in the lower part of the stomach,severe enterification,initial multiple lesions,and postoperative eCu-ra grade C have a higher risk of SGC and MGC after ESD,and the follow-up time should be extended.
Early gastric cancerEndoscopic submucosal dissectionSynchronous gastric cancerMetachronous gastric canc-erInfluencing factor
NETL
NSTL
万方数据
