Progress in the Study of Endogenous Hydrogen Sulfide Fluorescent Probes Based on AIE Effect
Rational design of fluorescent probe molecules for monitoring endogenous hydrogen sulfide(H2 S)can help to fully understand its physiological and pathological functions.Most of the small-molecule fluorescent probes currently under development for the detection of H2 S suffer from aggregation-caused quenching(ACQ)effect,and the study of aggregation-induced emission(AIE)probes that can overcome this deficiency has received increasing attention.In this paper,we briefly review the progress and design ideas of chemically reactive H2 S in vivo imaging fluorescent probes with AIE effect in recent years,with the aim of providing some reference and thoughts for research in this field.
endogenous hydrogen sulfideaggregation-caused quenching(ACQ)effectaggregation-induced emission(AIE)effectfluorescent probein vivo imaging