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加减身痛逐瘀汤提取液在红花籽油中的增溶研究

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本文以透明度和稳定性为评价标准,考察Span系列表面活性剂,Span80-Tween80复配表面活性剂在红花籽油中的溶解性能,通过对增溶后形成的体系中指标性成分龙胆苦苷、羌活醇、异欧前胡素的含量进行测定,研究Span80-Tween80复配表面活性剂对加减身痛逐瘀汤提取液在红花籽油中的增溶效果.结果表明,单一Span80表面活性剂和Span80-Tween80复配表面活性剂在质量比分别为9∶1、8∶2和7∶3时,能和红花籽油形成稳定透明的混合体系,复配表面活性剂对加减身痛逐瘀汤提取液的增溶能力随Span80相对量的增加而提高,其中Span80-Tween80质量比为9∶1时,增溶效果最好,增溶体系中龙胆苦苷、羌活醇和异欧前胡素的质量分数分别可达170.36 ×10-6、18.34×10-6和12.96 × 10-6.研究结果可为红花籽油的精深开发提供理论依据.
Study on Modified Shentong Zhuyu Decoction Extract Solubilization in Safflower Seed Oil
Taking the transparency and stability as evaluation criteria,the solubility of the surfactant Span series and Span80-Tween80 mixed surfactants in safflower seed oil was investigated.Through determination of the content of the indicator components gentiopiccrside,notopterol and isoimperatorn in the solubilized system,the solubilization capacity of Span80-Tween80 mixed surfactants on the modified Shentong Zhuyu decoction extract in safflower seed oil was studied.The results showed that the single surfactant Span80 and Span80-Tween80 mixed surfactants with a mass ratio of 9∶1,8∶2 and 7∶3 could form a stable and transparent mixed system with safflower seed oil.The solubilization capacity of the mixed surfactant on the extract increased with the increase of the relative amount of Span80.When the mass ratio of Span80-Tween80 was 9∶1,the solubilization capacity was the best,the mass fraction of gentiopiccrside,notopterol and isoimperatorn can reach 170.36 × 10-6,18.34× 10-6,12.96× 10-6.The research results provide a theoretical basis for the further in-depth development of safflower seed oil.

modified Shentong Zhuyu decoctionsolubilizationsafflower seed oil

刘凤霞、李文静、党利利、贺莉萍、张尚智

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甘肃中医药大学定西校区,甘肃定西 743000

加减身痛逐瘀汤 增溶 红花籽油

2024

辽宁大学学报(自然科学版)
辽宁大学

辽宁大学学报(自然科学版)

影响因子:0.371
ISSN:1000-5846
年,卷(期):2024.51(3)