Research Progress of Transition Metal-catalyzed Alkyne Carbon-Metallization Tandem Cyclization Reaction
The asymmetric functionalization of alkynes can be achieved by the addition reaction of alkynes with organic boron reagents catalyzed by transition metals and carbon-metallization tandem cyclization.Among them,arylboronic acids are most commonly used because of their high electrophilicity,high stability and wide source.In this paper,the research progress of various transition metal-catalyzed carbon-metallization tandem cyclization reactions of alkynes and arylboronic acids in recent years was reviewed.