Synthesis and Characterization of Ketoquinoline Derivatives
Potassium phthalimide was synthesized from phthalimide by reaction with KOH,then 4-bromomethylquinoline-2-one was synthesized by reaction with 4-bromomethylquinoline-2-one,and finally 4-aminomethylquinoline-2-one was obtained by reaction with DMF.Its structure was characterized by nuclear magnetic resonance,infrared spectroscopy and mass spectrometry.The optimum conditions of the reaction were determined by experiments,so as to solve the shortcomings of harsh reaction conditions,reduce the cost and improve the yield.
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