Study on Synthesis of 2-Phenyl-5-Chloromethyl-7-p-Toluidine Pyrazolo[1,5-a]Pyrimidine
Pyrazole[1,5-a]pyrimidine compounds are a class of nitrogen heterocyclic compounds with good biological activity,its molecules exist two kinds of important pyrazole and pyrimidine active unit,and thus these compounds show good biological activity,they are often widely used in medicine,pesticide,chemical and other related fields,to develop new type of antitumor drug,enzyme inhibition,fungicide,and herbicide,etc.In this paper,2-phenyl-5-chloromethyl-7-p-toluidine pyrazolo[1,5-a]pyrimidine was synthesized.The problems and solutions in the experiments were discussed,the synthetic route was explored and screened,the synthesis method was optimized.
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