增生性瘢痕和瘢痕疙瘩的发病机制与诊治进展
Advances in the pathogenesis,diagnosis and treatment of hypertrophic scars and keloids
杨斌1
作者信息
- 1. 南方医科大学皮肤病医院,广东 广州 510091
- 折叠
摘要
皮肤瘢痕是皮肤损伤所引起的皮肤组织外观形态和组织病理学改变的疾病,主要包括增生性瘢痕和瘢痕疙瘩.两种瘢痕的发病机制尚未完全阐明,其鉴别诊断主要依靠病史、临床特征以及皮损组织活检.治疗应建立在充分的瘢痕评估以及风险评估的基础上.目前,国内外专家针对增生性瘢痕和瘢痕疙瘩提出新的治疗方案,在药物、手术、光电以及放射治疗等方向皆有新的认识.本文主要综述增生性瘢痕和瘢痕疙瘩的发病机制及诊治进展,期待为瘢痕的诊治提供新思路.
Abstract
Skin scars,mainly including hypertrophic scars and keloids,are damage-induced diseases with changes in skin tissue appearance and histopathology.The pathogenesis of scars has not yet been fully elucidated and the differential diagnosis of scars mainly relies on medical histo-ry,clinical features and skin biopsy.The treatment should be based on adequate assessment of scar and risk.At present,domestic and abroad experts have proposed new treatment options for hypertrophic scars and keloids,and have new understandings of drugs,surgery,photoelectricity and radiation therapy.This article mainly reviews the progress in the diagnosis and treatment of hypertrophic scars and keloids in order to provide new ideas for the diagnosis and treatment of scars.
关键词
瘢痕/增生性瘢痕/瘢痕疙瘩/发病机制/治疗Key words
scar/hypertrophic scar/keloid/pathogenesis/treatment引用本文复制引用
出版年
2023