Application of anakinra in inflammatory dermatoses
Interleukin 1(IL-1)is an important cytokine,which is involved in the development of many inflammatory diseases.IL-1 inhibitors have become an effective approach in the treatment of these diseases.Anakinra is the first and the most widely used IL-1 inhibitor on the market.Studies have shown satisfactory efficacy in the treatment of some inflammatory dermatoses.This re-view mainly summarizes applications of anakinra in adult-onset Still's disease,Schnitzler syn-drome,hidradenitis suppurativa,pustular psoriasis,Bechet disease and pyoderma gangrenosum.