阿那白滞素在炎症性皮肤病中的临床应用
Application of anakinra in inflammatory dermatoses
游晓媚 1古甘霖 1江燕云 1王亮春1
作者信息
- 1. 中山大学孙逸仙纪念医院,广东 广州 510120
- 折叠
摘要
白细胞介素-1(IL-1)是一种重要的细胞因子,参与许多炎症性疾病的发病.IL-1抑制剂成为治疗这类疾病的有效方法.阿那白滞素(anakinra)是最早上市且应用最多的IL-1抑制剂,在一些炎症性皮肤病中显示出良好的疗效.本文主要就阿那白滞素在成人Still病、Schnitzler综合征、化脓性汗腺炎、脓疱型银屑病、白塞病、坏疽性脓皮病中的临床应用进行综述.
Abstract
Interleukin 1(IL-1)is an important cytokine,which is involved in the development of many inflammatory diseases.IL-1 inhibitors have become an effective approach in the treatment of these diseases.Anakinra is the first and the most widely used IL-1 inhibitor on the market.Studies have shown satisfactory efficacy in the treatment of some inflammatory dermatoses.This re-view mainly summarizes applications of anakinra in adult-onset Still's disease,Schnitzler syn-drome,hidradenitis suppurativa,pustular psoriasis,Bechet disease and pyoderma gangrenosum.
关键词
IL-1/IL-1抑制剂/阿那白滞素/炎症性皮肤病Key words
IL-1/IL-1 inhibitors/anakinra/inflammatory skin diseases引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据