首页|肥胖与银屑病关系的研究进展

肥胖与银屑病关系的研究进展

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肥胖是世界范围内的一个重大公共卫生问题,与慢性炎症及其相关并发症发展密切相关,如银屑病、2型糖尿病、高脂血症、动脉粥样硬化等.肥胖和银屑病可能受饮食习惯、免疫、微生物群以及环境等多因素影响,但具体机制尚未完全明了.肥胖与银屑病的发展密切相关,主要是因为肥胖与银屑病患者的脂肪因子会使促炎因子活化从而加重银屑病症状.肥胖是银屑病患者的重要危险因素之一.与正常体质量人群相比,超重或肥胖会加重银屑病患者病情.本文从流行病学、人体测量指标、微生物群、饮食、促炎因子、治疗等多角度综述肥胖与银屑病之间可能存在的联系.
Research progress in the relationship between obesity and psoriasis
Obesity is a major public health problem worldwide,which is linked to the develop-ment of chronic inflammation and its related complications,such as psoriasis,type 2 diabetes,hy-perlipidemia,atherosclerosis,etc.Obesity and psoriasis can be influenced by multiple factors,such as dietary habits,immune factors,microbiota and environmental factors,but the specific mechanisms are not yet clear.The link between obesity and psoriasis is mainly mediated by fat factors in obese and psoriatic patients,which can activate pro-inflammatory factors,thereby exac-erbating psoriasis symptoms.Obesity is one of the important risk factors for psoriatic patients.And compared to normal weight individuals,overweight or obesity can worsen psoriasis.This paper re-views the possible connections between obesity and psoriasis from multiple aspects,including epi-demiology,anthropometric indicators,microbiota,diet,pro-inflammatory factors and treatment.

obesitypsoriasisanthropometric indicatorsmicrobial communitydietpro-inflammatory factorstreatment

聂君儿、欧阳东成、谢琴、杨细飞

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南方医科大学公共卫生学院,广东 广州 510515

广东岭南职业技术学院,广东 广州 510640

广州华夏职业学院,广东 广州 510935

深圳市疾病预防控制中心深圳市现代毒理学重点实验室,深圳市卫生毒理学医学重点学科,广东 深圳 518020

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肥胖 银屑病 人体测量指标 微生物群 饮食 促炎因子 治疗

国家自然科学基金深圳市基础研究重点项目

82171583JCYJ20200109150717745

2024

皮肤性病诊疗学杂志
广东省皮肤性病防治中心

皮肤性病诊疗学杂志

影响因子:0.666
ISSN:1674-8468
年,卷(期):2024.31(1)
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