Research progress on the association of autophagy with invasion and metastasis of malig-nant melanoma
Autophagy is a unique biological phenomenon of eukaryotic cells.Autophagy plays a very important role in promoting the survival of cells and actively adapting to different environ-ments.Autophagy plays a double-edged role in the development of tumor and metastasis.The re-search results on the link between autophagy and melanoma are inconsistent,likely due to the in-trinsic heterogeneity of melanoma and the difference in methodology of detecting autophagy.How-ever,the results of studies on different aspects support a link between autophagy and malignant melanoma,especially the important role of autophagy in targeted drug therapy.This paper reviews the dual role of autophagy in the biological processes of melanoma invasion and metastasis,in or-der to provide clues for the development of new therapeutic regimens and biomarkers for malignant melanoma.
国家科技期刊平台
NSTL
万方数据
