报告1例脚趾鲍温病.患者女,39岁.左拇趾内侧皮肤红色斑块1月余.1月余前患者发现左拇趾内侧皮肤红斑丘疹,无自觉症状.外用糖皮质激素治疗无效.5～6年前曾于患处出现类似皮疹,并于外院进行手术切除,结果不详.皮肤科查体:左拇趾内侧皮肤可见一约1.5 cm × 1.5 cm浸润性红斑,略突出于皮面,边界较清楚;中央见0.5 cm ×0.3 cm左右暗红色痂壳.皮损组织病理检查显示表皮全层鳞状上皮异形增生.诊断:鲍温病.予等离子烧灼去除肉眼可见病灶后,5-氨基酮戊酸光动力治疗4次,皮损完全消退.电话随访1年无复发.
Bowen's disease of toe treated with plasma combined with photodynamic therapy:A case report and literature review
A case of Bowen's disease of toe is reported.A 39-year-old woman presented with red asymptomatic lesion on the medial side of the left big toe for over a month.Topical treatment with glucocorticoid was not effective.A similar rash appeared on the same area 5 to 6 years ago,and was surgically removed.Clinical examination revealed a demarcated red plaque 1.5 cm × 1.5 cm in diameter,with dark red crust in the center,on her big left toe.The histopathological exami-nation of the skin lesion showed heteroplasia of the squamous epithelium in the epidermis.The di-agnosis was Bowen's disease.Following removal of lesion with electrocauterization,5-aminolevu-linic acid photodynamic(ALA-PDT)was given 4 times.The lesion completely subsided with no re-currence during 1-year telephone follow-up.
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