Progress in the diagnosis and treatment of mycosis fungoides with large cell transformation
Mycosis fungoides is a non-Hodgkin lymphoma originating from skin-resident memo-ry helper T cells,representing the most common subtype of cutaneous T-cell lymphoma.Large cell transformation is a unique form of primary cutaneous T-cell lymphoma with unclear etiology and pathogenesis.Clinical manifestations and auxiliary examinations lack specificity.Whether patients need aggressive treatment is controversial.This article systematically reviews the etiology,patho-genesis,clinical manifestations,diagnosis,treatment,and prognosis of mycosis fungoides with large cell transformation,offering insights for its diagnosis and management.
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