Research progress on function and evolution of heat shock protein
Heat shock protein(HSP)is a kind of protein produced when organisms are stimulated by external physical,chemical,environment or stressed by heat shock,infection and others.In addition to this expression,there is constitutive expression of heat shock protein.Heat shock proteins are u-biquitous in various organisms and play an important role as a molecular chaperone in biological pro-tein folding,transport and expression.Although most heat shock proteins are highly conserved across species,a few HSPs are also different in evolution,indicating that HSPs has different func-tions in different species.Recently,heat shock proteins have attracted attention in the fight against diseases(such as tumor,atherosclerosis and COVID-19,etc.)and in drug research and development.This paper reviews the function and evolution of HSPs proteins in recent years,which is expected to improve the related research of HSPs.