首页|猪源链球菌对β-内酰胺类抗生素的耐药性研究进展

猪源链球菌对β-内酰胺类抗生素的耐药性研究进展

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猪链球菌病是生猪养殖中比较常见且危害较大的动物疫病,该病的病原是球菌科链球菌属的多种链球菌,其中猪链球菌2型是重要的人畜共患病原菌.β-内酰胺类抗生素一直是治疗猪链球菌病的首选药物,但受长期选用的影响,猪源链球菌对β-内酰胺类抗生素的耐药性逐渐增强,给猪链球菌病的临床治疗带来威胁.文章对猪链球菌病的流行性及病原特点、猪源链球菌对β-内酰胺类抗生素的耐药机制和耐药现状进行概述,以期为指导临床用药和新药研发提供参考.
Research progress on drug resistance of Streptococcus suis to β-lactam antibiotics
Streptococcus suis is a common and harmful animal disease in pig breeding.The pathogen of this disease is a variety of streptococci of Streptococcus of Coccidae,among which Streptococcus suis type 2 is an important zoonotic pathogen.β-lactam antibiotics have always been the first choice for the treatment of Streptococcus suis.However,due to the long-term selection,the resistance of Streptococcus suis to β-lactam antibiotics has gradually increased,which poses a threat to the clinical treatment of Streptococcus suis.In the paper,the epidemic and pathogenic characteristics of Streptococcus suis,the resistance mechanism,and current situation of Streptococcus suis to β-lactam antibiotics were summarized,in order to provide a reference for guiding clinical medication and new drug research and development.

Streptococcus suisβ-lactam antibioticsDrug resistanceDrug resistance mechanism

散仁、董鹏、朝博、红英、杨洺扬

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通辽市农畜产品质量安全中心,内蒙古 通辽 028000

通辽市动物检疫技术服务中心,内蒙古 通辽 028000

中国农业科学院草原研究所,内蒙古 呼和浩特 010010

库伦镇综合保障和技术推广中心,内蒙古 通辽 028000

辽宁省农业发展服务中心,辽宁 沈阳 110164

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猪源链球菌 β-内酰胺类抗生素 耐药性 耐药机制

2024

现代畜牧兽医
辽宁省畜牧兽医学会 辽宁省动物卫生监测预警中心

现代畜牧兽医

影响因子:0.316
ISSN:1672-9692
年,卷(期):2024.(4)