猪源链球菌对β-内酰胺类抗生素的耐药性研究进展
Research progress on drug resistance of Streptococcus suis to β-lactam antibiotics
散仁 1董鹏 2朝博 3红英 4杨洺扬5
作者信息
- 1. 通辽市农畜产品质量安全中心,内蒙古 通辽 028000
- 2. 通辽市动物检疫技术服务中心,内蒙古 通辽 028000
- 3. 中国农业科学院草原研究所,内蒙古 呼和浩特 010010
- 4. 库伦镇综合保障和技术推广中心,内蒙古 通辽 028000
- 5. 辽宁省农业发展服务中心,辽宁 沈阳 110164
- 折叠
摘要
猪链球菌病是生猪养殖中比较常见且危害较大的动物疫病,该病的病原是球菌科链球菌属的多种链球菌,其中猪链球菌2型是重要的人畜共患病原菌.β-内酰胺类抗生素一直是治疗猪链球菌病的首选药物,但受长期选用的影响,猪源链球菌对β-内酰胺类抗生素的耐药性逐渐增强,给猪链球菌病的临床治疗带来威胁.文章对猪链球菌病的流行性及病原特点、猪源链球菌对β-内酰胺类抗生素的耐药机制和耐药现状进行概述,以期为指导临床用药和新药研发提供参考.
Abstract
Streptococcus suis is a common and harmful animal disease in pig breeding.The pathogen of this disease is a variety of streptococci of Streptococcus of Coccidae,among which Streptococcus suis type 2 is an important zoonotic pathogen.β-lactam antibiotics have always been the first choice for the treatment of Streptococcus suis.However,due to the long-term selection,the resistance of Streptococcus suis to β-lactam antibiotics has gradually increased,which poses a threat to the clinical treatment of Streptococcus suis.In the paper,the epidemic and pathogenic characteristics of Streptococcus suis,the resistance mechanism,and current situation of Streptococcus suis to β-lactam antibiotics were summarized,in order to provide a reference for guiding clinical medication and new drug research and development.
关键词
猪源链球菌/β-内酰胺类抗生素/耐药性/耐药机制Key words
Streptococcus suis/β-lactam antibiotics/Drug resistance/Drug resistance mechanism引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据