Research progress of major secreted proteins during Toxoplasma gondii invasion
Toxoplasma gondii is an obligate intracellular parasite of the parietal phylum.The parasite uses a series of secreted proteins to complete its invasion of the host.Key proteins involved in Toxoplasma gondii's host invasion process include:Microfilament proteins(MICs)at the front end,which participate in the formation of apical complex;Rod body proteins(ROPs),which help to establish intracellular environment;Dense particle proteins(GRAs),which regulate multiple steps in the invasion process.In the paper,the main secreted proteins during the invasion of Toxoplasma gondii were summarized,and the future development of Toxoplasma gondii vaccine was prospectively considered,in order to provide a reference for exploring the pathogenic principle of Toxoplasma gondii and developing vaccines.
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