Evaluation of the health care effects of Bupleurum extract on major metabolic diseases in periparturient dairy cows
The experiment aimed to clarify the effects of Bupleurum extract on the blood biochemical indicators,metabolic disease incidence,antioxidant capacity,and milk quality in periparturient dairy cows.Fourteen healthy cows were randomly selected 21 days before parturition and divided into two groups,which were administered either 0.06 kg/(cow·day)of Bupleurum extract via intramuscular injection for three consecutive days(treatment group)or an equal volume of physiological saline(control group).The trial period was 42 days.The results showed that on 21 and 28 days after postpartum,the plasma glucose(GLU)contents in the cows of the treatment group were significantly higher than those in the control group(P<0.05).Compared with the control group,the incidence of ketosis and fatty liver in the treatment group was reduced,but the incidence of subclinical hypocalcemia increased.On the day of delivery and 14 and 21 days after postpartum,the plasma triglyceride(TG)contents in the treatment group were significantly higher than those in the control group(P<0.05).21 days after postpartum,the plasma high-density lipoprotein cholesterol(HDL-C)contents in the treatment group were significantly higher than those in the control group(P<0.05).7 and 14 days after postpartum,the superoxide dismutase(SOD)activity in the plasma of the treatment group was significantly higher than that in the control group(P<0.05).14 days after postpartum,the total antioxidant capacity(T-AOC)and catalase(CAT)activity in the plasma of the treatment group was significantly higher than that in the control group(P<0.05).The study indicates that the injection of Bupleurum extract can effectively improve the antioxidant capacity of dairy cows,improve hepatic lipid metabolism,reduce the incidence of fatty liver and ketosis in dairy cows,but increases the incidence of subclinical hypocalcemia.
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