The experiment aimed to understand the infection status of wild pseudorabies virus(PRV)and the level of immune antibodies in pig populations in some regions of Xinjiang from 2022 to 2023.An enzyme-linked immunosorbent assay(ELISA)kit was used to test for antibodies against two proteins,PRV-gE and PRV-gB,in 510 serum samples from 13 large-scale pig farms in six regions of Xinjiang.The results showed that from 2022 to 2023,the average positive rate of PRV-gE protein antibodies in some regions of Xinjiang was 21.76%(111/510),with significant differences in the average positive rates of PRV-gE protein antibodies among different regions and large-scale pig farms.The average positive rate of PRV immune antibodies in large-scale pig farms in the Xinjiang region was 59.41%(303/510),which is lower than the national standard(70%).Only 38.46%(5/13)of the pig farms reached the national standard for immune antibody positivity,with significant differences in PRV immune antibody positive rates among different regions and large-scale pig farms.The study indicates that from 2022 to 2023,the infection rate of PRV wild virus in some regions of Xinjiang remains at a high level,with a low rate of immune compliance,posing a significant risk,and there is a need to strengthen immunization and prevention measures against PRV.