首页|绵羊和山羊多能干细胞的研究进展和应用前景

绵羊和山羊多能干细胞的研究进展和应用前景

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多能干细胞可以无限增殖,通过分化生成三胚层各种细胞,因而广泛应用于再生医学、疾病建模等方面的研究.绵羊和山羊多能干细胞具有多向分化潜能,细胞增殖率高.因此,通过利用多能干细胞育种技术可大大缩短羊育种时间,进而达到生产优质高产羊品种的目的.文章总结了绵羊和山羊胚胎干细胞与诱导多能干细胞的研究进展,并对近年来绵羊和山羊多能干细胞在生物学基础研究、动物遗传育种、医学疾病建模等领域的应用前景进行了展望,以期为羊育种方向的研究提供参考.
Research progress and application prospect of pluripotent stem cells in sheep and goats
Pluripotent stem cells can proliferate indefinitely and generate various cells in three layers through differentiation,so they are widely used in research of regenerative medicine,disease modeling.Sheep and goat pluripotent stem cells have multidirectional differentiation potential and high cell proliferation rate.Therefore,the breeding time of sheep can be greatly shortened by using pluripotent stem cell breeding technology,so as to achieve the purpose of producing high-quality and high-yield sheep breeds.This paper summarized the research progress of embryonic stem cells and induced pluripotent stem cells of sheep and goats,and prospected the application prospect of pluripotent stem cells of sheep and goats in basic biological research,animal genetic breeding,medical disease modeling and other fields in recent years,in order to provide reference for the research of sheep breeding.

SheepGoatPluripotent stem cells

冯娜、刘小东、高瀚洋、李娜娜、曹凯鑫、李宜璇

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榆林市羊产业发展中心,陕西 榆林 719000

渭南市富平县宫里镇人民政府,陕西 渭南 714000

绵羊 山羊 多能干细胞

2024

现代畜牧兽医
辽宁省畜牧兽医学会 辽宁省动物卫生监测预警中心

现代畜牧兽医

影响因子:0.316
ISSN:1672-9692
年,卷(期):2024.(10)