2型糖尿病与甲状腺结节关系的研究进展
Research progress on the relationship between type 2 diabetes mellitus and thyroid nodules
齐天莹 1张汝轩 1周新丽1
作者信息
- 1. 山东大学,山东济南 250100;山东第一医科大学附属省立医院(山东省立医院)内分泌代谢病科,山东济南 250021;山东省糖尿病与代谢疾病临床医学研究中心,山东济南 250021;山东省内分泌与代谢病研究所,山东济南 250021
- 折叠
摘要
近年来,2型糖尿病与甲状腺结节的发病率不断增高,作为内分泌代谢系统中最常见的两大疾病,二者密切相关.有研究显示,2型糖尿病与甲状腺结节的发病风险有一定的相关性.根据流行病学显示,2型糖尿病可能会增加甲状腺结节的发生风险,促进甲状腺结节的发生发展.有证据表明,将甲状腺结节和2型糖尿病联系起来的因素包括性别、年龄、肥胖、高血糖和胰岛素抵抗等,其潜在机制包括甲状腺激素水平异常、胰岛素的影响、炎症和脂肪细胞因子的作用,此外,某些降糖药物还具有抗甲状腺结节的作用.
Abstract
In recent years,the incidence of type 2 diabetes mellitus and thyroid nodules has been continuously in-creasing.As the two most common diseases in the endocrine metabolic system,they are closely related.Research has shown that there is a certain correlation between type 2 diabetes mellitus and the risk of thyroid nodules.According to epi-demiological studies,type 2 diabetes mellitus may increase the risk of thyroid nodules and promote their occurrence and development.Evidence suggests that factors linking thyroid nodules and type 2 diabetes mellitus include gender,age,obe-sity,high blood sugar,and insulin resistance.The underlying mechanisms include abnormal thyroid hormone levels,the impact of insulin,inflammation,and the role of adipokines.Additionally,certain ahypoglycemic drugs also have a role in countering thyroid nodules.
关键词
2型糖尿病/甲状腺结节/炎症因子/胰岛素抵抗/甲状腺激素/降糖药物Key words
type 2 diabetes mellitus/thyroid nodule/inflammatory factor/insulin resistance/thyroid hormones/hypoglycemic drugs引用本文复制引用
出版年
2024
NETL
NSTL
万方数据