Analysis of characteristics of nerve conduction velocity in elderly patients with diabetes peripheral neuropathy in a Grade Ⅲ and Class A hospital in eastern China
Objective To analyze the characteristics of nerve conduction velocity in elderly patients with diabetic pe-ripheral neuropathy(DPN),and discuss its application value.Methods The clinical data of 338 elderly patients with diabetes who visited the Department of Endocrinology of Huadong Hospital Affiliated to Fudan University from March 2022 to June 2023 were analyzed retrospectively.They were divided into research group(n =220)and control group(n =118)based on whether the results of their neurophysiological examination were abnormal.The motor nerve conduction velocity(MNCV),distal mo-tor latency(DML),proximal motor latency(PML),distal wave amplitude and proximal wave amplitude of median nerve,ul-nar nerve and common peroneal nerve were compared between the two groups.The sensory nerve conduction velocity(SNCV),latency and amplitude of median nerve,ulnar nerve and superficial peroneal nerve were compared between the two groups.The F-wave latency of ulnar nerves was also compared between the two groups.The abnormal rates of motor nerve conduction and distal wave amplitude in the research group were analyzed,and the abnormal rate of sensory nerve conduction and wave amplitude were analyzed.Results Compared with the control group,the MNCV of the median nerve of the research group was slower,DML and PML were longer,and the distal wave amplitude was smaller,and the differences were statistical-ly significant(P＜0.05);the MNCV of the ulnar nerve and common peroneal nerve of the research group was slower,DML and PML were longer,and distal and proximal wave amplitudes were smaller,and the differences were statistically significant(P＜0.05).Compared with the control group,the research group had a longer F-wave latency of the ulnar nerve[(26.02±2.02)ms vs(27.75±2.78)ms,P =0.167],and the difference was statistically significant.There were statistically significant differences in the abnormal rates of motor nerve conduction and sensory nerve conduction among different nerves in the research group;the abnormal rate of distal motor nerve conduction amplitude and sensory nerve conduction amplitude.Conclusion Elderly DPN patients have slower nerve conduction velocity,longer latency,and smaller wave amplitude.The re-sults of nerve conduction velocity detection may vary depending on the nerve selected.
国家科技期刊平台
NSTL
万方数据
维普
