Analysis of death factors within 30 days after acute pulmonary embolism in elderly patients
Objective To explore the influence factors of death within 30 days in elderly patients with acute pulmonary embolism(APE),and evaluate the predictive value of various factors in the prognosis of APE.Methods A total of 88 elderly APE patients(aged≥60 years)admitted to Central Hospital of Jing'an District from January 2021 to May 2023 were included in this study by retrospective analysis.Risk stratification was performed based on whether shock,hypotension,cardiac dysfunction,and elevated cardiac biological indicators were present at the onset of the disease.Their clinical vital signs and laboratory data were recorded,and their survival status was followed up within 30 days after diagnosis of APE.According to whether the patients survived after 30 days,they were divided into survival group and death group,and various data of the two groups were compared and analyzed.Results Among the 88 patients included,there were statistically significant differences in age,mean heart rate,mean systolic blood pressure,mean platelet volume(MPV),D-dimer/fibrinogen ratio(DFR)and risk stratification of pulmona-ry thromboembolism between the survival group and the death group(P＜0.05).Univariate logistic regression analysis showed that age,mean heart rate,lower limb venous thrombosis,MPV,DFR,and pulmonary thromboembolism risk stratification were the influencing factors for all-cause death in APE patients within 30 days(P＜0.05).Multivariate logistic regression analysis showed that MPV,DFR and pulmonary thromboembolism risk stratification were independent predictors of all-cause death within 30 days in APE patients(P＜0.05).In the prediction of all-cause death within 30 days in elderly APE patients,the area under re-ceiver operating characteristic curve(AUC)of MPV,DFR and pulmonary thromboembolism risk stratification alone and com-bined diagnosis were 0.762,0.839,0.821 and 0.926,respectively.Conclusion MPV,DFR and pulmonary thromboembolism risk stratification can serve as independent predictors of short-term prognosis in elderly APE patients.The combined assessment of the three indexes has a high predictive value for all-cause death within 30 days in elderly APE patients.
elderlyacute pulmonary embolismall-cause deathpulmonary thromboembolism risk stratificationmean platelet volumeD-dimer/fibrinogen ratio
国家科技期刊平台
NSTL
万方数据
维普
