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老年带状疱疹患者临床特点分析

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目的 分析老年带状疱疹患者的临床特征,为老年带状疱疹的预防和治疗提供依据.方法 采用回顾性分析方法,对2018 年1 月—2023 年8 月复旦大学附属华山医院皮肤科收治的 260 例老年带状疱疹患者的临床资料进行分析.结果 260例患者中,最常见的诱发因素是劳累,共 45 例(17.31%);最易发病部位为三叉神经支配区域,共 100 例(38.46%);疼痛性质多种多样,急性期疼痛以中重度疼痛为主,共 169 例(65.00%),其中 139 例(53.46%)患者皮疹发生前已感受到疼痛;合并症主要有高血压106 例(40.77%)、糖尿病 39 例(15.00%)和恶性肿瘤 17 例(6.54%);8 例患者早期被误诊,误诊率为3.08%;最常见且最严重的并发症为后遗神经痛,共51 例(19.62%).进一步分析发现,患者的年龄、急性疼痛的程度、发疹后启动治疗的时间、合并恶性肿瘤是老年人后遗神经痛发生的独立危险因素(P均<0.05).结论 老年带状疱疹患者发病率高、症状重、合并症多,容易发生后遗神经痛,应尽早进行诊断和个体化治疗,减少并发症发生,提高生活质量.
Analysis of clinical characteristics of elderly patients with herpes zoster
Objective To analyze the clinical characteristics of elderly patients with herpes zoster,and provide a basis for the prevention and treatment of herpes zoster.Methods A retrospective analysis method was used to analyze the clinical data of 260 elderly patients with herpes zoster admitted to Department of Dermatology of Huashan Hospital Affiliated to Fudan University from January 2018 to August 2023.Results Among 260 patients,the most common triggering factor was fatigue,with a total of 45 cases(17.31% );the most susceptible site of the disease was the area innervated by the trigeminal nerve,with a total of 100 cases(38.46% ).The nature of pain was diverse.The degree of pain was mainly moderate to severe during the acute phase,with a total of 169 cases(65.00% ),of which139 cases(53.46% )had already felt pain before the onset of rash.The main complications included106 cases of hypertension(40.77% ),39 cases of diabetes(15.00% )and17 cases of malignant tumors(6.54% ).8 patients were misdiagnosed early,and the misdiagnosis rate was3.08% .The most common and severe complication was postherpetic neuralgia,with a total of 51 cases(19.62% ).Further analysis showed that the age,degree of acute pain,time to initiate treatment after rash onset,and concomitant malignant tumor were independent risk factors for the occurrence of posthumous neuralgia in the elderly(all P<0.05).Conclusion Elderly patients with herpes zoster have a high incidence,severe symptoms and more complications,and they are prone to posthumous neuralgia.Therefore,early di-agnosis and individualized treatment should be carried out to reduce the occurrence of complications and improve quality of life.

elderlyherpes zosterclinical characteristicpostherpetic neuralgia

秦海红、刘晓、陈荪轶、吴金峰

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复旦大学附属华山医院皮肤科,上海 200040

老年 带状疱疹 临床特点 后遗神经痛

2024

老年医学与保健
复旦大学附属华东医院

老年医学与保健

CSTPCD
影响因子:0.655
ISSN:1008-8296
年,卷(期):2024.30(1)
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