Effects of atrial fibrillation on prognosis of elderly patients with coronary heart disease
Objective To explore the effects of atrial fibrillation(AF)on prognosis of elderly patients with coronary heart disease(CHD).Methods The clinical data of 219 elderly CHD patients admitted to Department of Cardiology,Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University from January 2020 to December 2020 were ret-rospectively analyzed.They were divided into MACE group(n =59)and non-MACE group(n =160)according to the occur-rence of major adverse cardiovascular events(MACE).The general data,serological indexes,echocardiographic parameters and coronary lesions were compared between the two groups.Kaplan-Meier curve was used to analyze the incidence of MACE in elderly CHD patients within 2 years.Cox proportional risk model was used to analyze the influencing factors for MACE in elderly CHD patients.Results Compared with the non-MACE group,the MACE group had lower level of high-density lipoprotein cho-lesterol,higher level of uric acid,and higher proportion of AF,with statistically significant differences(P＜0.05).Kaplan-Meier survival analysis showed that the 2-year survival time of AF patients without MACE was shorter than that of the non-AF patients[(17.16±1.03)months vs(21.30±0.48)months,P＜0.001].The Cox proportional risk model showed that elevated uric acid level and concomitant AF were risk factors for MACE in elderly CHD patients(P＜0.05).Conclusion Elderly CHD patients with high uric acid level or concomitant AF may be more prone to MACE.
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