Clinical observation on the treatment of vestibular migraine in elderly patients with traditional Chinese medicine syndrome dif-ferentiation therapy
Objective To observe the effectiveness of traditional Chinese medicine(TCM)syndrome differentiation therapy in improving clinical symptoms of of elderly patients with vestibular migraine.Method The clinical data of 122 elder-ly patients with vestibular migraine treated in Integrated Traditional Chinese and Western Medicine Hospital of Suzhou City from October 2021 to December 2023 were retrospectively collected.They were divided into control group and observation group based on whether TCM syndrome differentiation therapy was used.The control group received routine treatment,while the ob-servation group received TCM syndrome differentiation therapy in addition to routine treatment.The levels of serum calcitonin gene-related peptide(CGRP)and 5-hydroxytryptamine(5-HT)before and after treatment were detected and compared between the two groups.The changes of Dizziness Disorder Inventory(DHI)score,headache score and TCM syndrome score of the two groups were evaluated.The adverse reactions and recurrence of dizziness were recorded and compared between the two groups.The correlation among DHI score,headache score and TCM syndrome score was analyzed.Results There was no sta-tistically significant difference in the levels of serum CGRP and 5-HT between the two groups before treatment(P>0.05).Af-ter treatment,the serum CGRP levels of both groups were lower than those of the same group before treatment,while serum 5-TH levels were higher than those of the same group before treatment(P<0.05).The serum CGRP level of the observation group after treatment was lower than that of the control group,and the serum 5-TH level was higher than that of the control group,with statistical significances(P<0.05).After treatment,the number of recurrent dizziness in the observation group was significantly lower than that in the control group(P<0.05).There was no statistically significant difference in DHI score,headache score,and TCM syndrome score between the two groups before treatment(P>0.05).After treatment,the DHI score,headache score,and TCM syndrome score of the two groups were lower than those of the same group before treatment,while the DHI score,headache score,and TCM syndrome score of the observation group were lower than those of the control group(P<0.05).DHI score and headache score were positively correlated with TCM syndrome score(P<0.05).Conclusion TCM syndrome differentiation therapy can effectively alleviate the clinical symptoms of elderly patients with ves-tibular migraine,and has certain clinical application value.
elderlyvestibular migrainetraditional Chinese medicine syndrome differentiation therapydizzinesscal-citonin gene-related peptideserotonin