Investigation of enteral feeding intolerance and its influencing factors in elderly emergency patients with septic shock
Objective To analyze enteral feeding intolerance(EFI)and its influencing factors in elderly emergency pa-tients with septic shock.Methods The clinical data of 116 elderly emergency patients with septic shock treated in First People's Hospital of Huai'an City Huai'an from June 2020 to June 2023 were retrospectively analyzed.Their EFI status was in-vestigated.They were divided into enteral feeding tolerance group(n=60)and EFI group(n=56)according to whether en-teral feeding was tolerated.The influencing factors of EFI in elderly emergency patients with septic shock were analyzed.Results Among 116 elderly emergency patients with septic shock,EFI occurred in 56 cases(48.28%).There were signifi-cant differences in catheterization methods,types of main underlying diseases,total number of infection sites,types of patho-gens,APACHE Ⅱ score,enteral nutrition regimens,types of used antibiotics,analgesics,hypoalbuminemia,start time of en-teral nutrition and use of probiotics between the two groups(P<0.05).Binary logistic regression analysis showed that total number of infection sites ≥2(OR=2.280,95%CI:1.091~4.763),mixed infection(OR=2.651,95%CI:1.093~6.430),APACHE Ⅱ score>20 points(OR=2.425,95%CI:1.034~5.689),types of used antibiotics ≥3(OR=2.102,95%CI:1.059~4.175),hypoalbuminemia(OR=2.875,95%CI:1.151~7.180)and start time of enteral nutrition>7 d(OR=2.445,95%CI:1.020~5.860)were all ri sk factors of EFI in elderly emergency patients with septic shock(P<0.05).Conclusion The incidence of EFI is higher in elderly emergency patients with septic shock.The total number of infec-tion sites,types of pathogens,APACHE Ⅱ score,types of used antibiotics,hypoalbuminemia and start time of enteral nutrition may be the influencing factors of EFI in elderly emergency patients with septic shock.