首页|SARC-F筛查肌少症效能的优化研究

SARC-F筛查肌少症效能的优化研究

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目的 探讨SARC-F筛查肌少症效能的优化方法.方法 2018年3月-2021年8月,采用SARC-F评分量表、AWGS2和EWGSOP2诊断共识对受试者进行肌少症诊断,分析诊断一致性,优化SARC-F筛查肌少症的效能.结果 以SARC-F、AWGS2 和 EWGSOP2 诊断的肌少症患病率分别为 12.78%(52/407)、28.26%(115/407)和 31.20%(127/407).以AWGS2和EWGSOP2为金标准,SARC-F≥4分筛查肌少症的灵敏度为37.39%(43/115)和35.43%(45/127),特异度为96.92%(283/292)和97.50%(273/280).受试者操作特征曲线显示,SARC-F的最优诊断截断值为2分.SARC-F≥2 分筛查肌少症的灵敏度为 89.57%(103/115)和 88.98%(113/127),特异度为 76.71%(224/292)和79.29%(222/280).结论 SARC-F≥2分诊断肌少症可能具有更高的灵敏度,更适用于初步筛查.
A study on optimization of SARC-F screening efficacy for sarcopenia
Objective To explore an optimization method of SARC-F screening efficacy for sarcopenia.Methods From March 2018 to August 2021,the SARC-F scoring scale,Asian Working Group for Sarcopenia 2(AWGS2)and European Working Group on Sarcopenia in Older People 2(EWGSOP2)were used to diagnose sarcopenia in the subjects.Results The prevalence of sarcopenia diagnosed by SARC-F,AWGS2 and EWGSOP2 were 12.78%(52/407),28.26%(115/407)and 31.20%(127/407),respectively.Taking AWGS2 and EWGSOP2 as the gold criteria,the sensitivity of SARC-F ≥4 for screening sarcopenia was 37.39%(43/115)and 35.43%(45/127),and the specificity was 96.92%(283/292)and 97.50%(273/280).Receiver operator characteristic curve showed that the optimal cut-off value of SARC-F was 2 points.The sensitiv-ity of SARC-F≥ 2 for screening sarcopenia was 89.57%(103/115)and 88.98%(113/127),and the specificity was 76.71%(224/292)and 79.29%(222/280).Conclusion SARC-F≥2 may have higher sensitivity for diagnosing sarcopenia and is more suitable for initial screening.

elderlysarcopeniadiagnostic criteriaprevalence

刘陪沛、王芳、曹梦宇、徐率轩、张倪惠、刘金炜、陈超、彭楠

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中央军委机关事务管理总局,北京 100034

中国人民解放军总医院第二医学中心康复医学科,国家老年疾病临床医学研究中心,北京 100853

解放军医学院研究生院,北京 100853

老年人 肌少症 诊断标准 患病率

国家重点研发计划

2018YFC2002004

2024

老年医学与保健
复旦大学附属华东医院

老年医学与保健

CSTPCD
影响因子:0.655
ISSN:1008-8296
年,卷(期):2024.30(4)