Study on activation of cortical areas related to swallowing in elderly populationunder different taste stimulation
Objective To explore the effects of different taste stimulation on activation of different functional areas of cerebral cortex in elderly population based on functional near-infrared spectroscopy(fNIRS).Methods Nineteen elderly par-ticipants(mean age:70.7±7.2 years)who underwent health examinations in The First Rehabilitation Hospital of Shanghai from January to March 2023 were enrolled.When they swallowed spicy solution,sour solutionand and distilled water,fNIR-Simaging technologywas used to record the concentrations of oxygenated hemoglobin(HbO2)in bilateral prefrontal lobes and bilateral motor areas.The differences in cortical activation patterns of subjectsunder different taste swallowing tasks were ana-lyzed.Results When swallowing sour and spicy solutions,it could significantly activate the supramarginal gyrus part,premo-tor cortex and supplementary motor area,dorsolateral prefrontal cortex,posterior inferior frontal gyrus,frontopolar area,and inferior prefrontal gyrus(P＜0.05).The sour solution also significantly activated the right primary motor cortex(P＜0.05).Compared with swallowing distilled water,swallowing sour solution significantly activated the right supramarginal gyrus part(P＜0.05),bilateral pre-motor cortex and supplementary motor area(P＜0.05),right dorsolateral prefrontal lobe(P＜0.05),bilateral frontopolar area(P＜0.05),and right inferior prefrontal gyrus(P＜0.01).Compared with swallowing spicy solution,swallowing sour solution significantly activated the right inferior prefrontal gyrus(P＜0.05).Conclusion Different taste stimulation can affect the activation of the cerebral cortex related to swallowing in elderly population.Sour taste stimula-tion can promote the activation of the right primary motor cortex,which may have potential application value for the prevention and treatment of swallowing disorders in elderly people.
国家科技期刊平台
NSTL
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