Analysis of prognostic factors in elderly patients with bronchiectasis
Objective To analyze the adverse prognostic factors of elderly patients with bronchiectasis,and provide ide-as for their clinical diagnosis and treatment.Methods 150 elderly patients with bronchiectasis who received treatment in Bei-jing Rehabilitation Hospital Affiliated to Capital Medical University from January 2021 to September 2023 were retrospectively selected.Their clinical baseline data,laboratory indicators,lung function were recorded.Their efficacy and death during the follow-up period were recorded.The patients who were admitted to hospital because of acute attack again or died within 90 days after discharge were included in the poor prognosis group,and the remaining patients were included in the good prognosis group.Results There were no significant differences in age,sex,BMI,arm circumference,histories of smoking,diabetes,hypertension,coronary heart disease and bronchial asthma,the levels of serum WBC,Hb,neutrophil,platelet count,eosino-phils,blood gas indices(PaCO2,PaO2,pH)and FEV1/FVC ratio between the two groups(P＞0.05).There were signifi-cant differences in the course of disease,histories of hemoptysis and pulmonary tuberculosis,concomitant COPD,thickness of umbilical subepithelial fat,the levels of serum ALB,FEV1％pred and FVC between the two groups(P＜0.05).Multivariate logistic regression analysis showed that the thickness of umbilical subepithelial fat[OR=3.153,95％CI=(1.335-7.502)],FEV1％pred[OR=6.022,95％CI=(1.890-14.254)],history of hemoptysis[OR=4.817,95％CI=(1.455-9.659)],history of pulmonary tuberculosis[OR=4.135,95％CI=(1.419-8.224)]and ALB level[OR=2.853,95％CI=(1.109-6.830)]were independent influencing factors for poor prognosis(P＜0.05).Conclusion There are many factors affecting the poor prognosis of patients.In clinical practice,targeted intervention measures should be taken according to their past medi-cal history,nutritional status,lung function,etc.to improve their prognosis.
elderlybronchiectasisprognosisinfluencing factornutrient levellung functionpast medical history
万方数据
维普
