辽宁医学杂志2024,Vol.38Issue(1) :20-23.

银杏达莫注射液联合溶栓对老年缺血性卒中患者疗效研究

Effect of Ginkgo Leaf Extract and Dipyridamole Injection Combined with Thrombolysis on Elder-ly Patients with Ischemic Stroke

梁利超
辽宁医学杂志2024,Vol.38Issue(1) :20-23.

银杏达莫注射液联合溶栓对老年缺血性卒中患者疗效研究

Effect of Ginkgo Leaf Extract and Dipyridamole Injection Combined with Thrombolysis on Elder-ly Patients with Ischemic Stroke

梁利超1
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作者信息

  • 1. 南乐县人民医院(河南濮阳 457400)
  • 折叠

摘要

目的 探讨银杏达莫注射液联合溶栓对老年缺血性卒中患者疗效研究.方法 选取我院2019年10月~2021年10月收治的96例老年缺血性卒中患者.随机将96例患者分为观察组与对照组,其中48例观察组患者入院后实施银杏达莫注射液联合溶栓(阿替普酶)治疗,48例对照组患者入院后仅实施阿替普酶治疗.比较两组患者治疗后临床疗效,利用中国卒中神经功能评分量表(Css)评估两组患者治疗前后神经功能情况,利用日常生活活动能力量表(ADL)评估两组患者治疗前后日常生活活动能力情况.结果 治疗后观察组总有效47例(97.72%),对照组总有效41例85.42%,两组比较差异有统计学意义(x2=4.909,P=0.027);治疗后患者CSS分值均降低,ADL分值均升高(P<0.05),且观察组患者CSS(10.68±2.76)分低于对照组CSS(15.69±2.73)分(t=8923,P<0.05),ADL(68.97±10.28)分高于对照组 ADL(56.44±11.49)分(t=6.529,P<0.05).结论 银杏达莫注射液与阿替普酶静脉溶栓联合治疗老年缺血性卒中患者疗效显著,能显著增强患者日常生活能力,改善神经功能,具有一定临床价值.

Abstract

Objective To investigate the effect of Ginkgo Leaf Extract and Dipyridamole Injection combined with throm-bolysis on elderly patients with ischemic stroke.Methods Ninety-six elderly patients with ischemic stroke admitted to our hospital from October 2019 to October 2021 were selected and randomly divided into an observation group(n=48)treated with Ginkgo Leaf Extract and Dipyridamole Injection combined with thrombolysis(alteplase),and a control group(n=48)treated with alteplase only after admission.The clinical efficacy were compared between the two groups.The Chinese Stroke Neurological Scale(CSS)was used to assess the neurological function of the two groups before and after treatment,and the Activities of Daily Living Scale(ADL)was used to assess the activities of daily living of the two groups before and after treatment.Results After treatment,47 cases(97.72%)were effective in the observation group,and 41 cases(85.42%)in the control group.There was significant difference between the two groups(x2=4.909,P=0.027).After treatment,the CSS scores of the patients were decreased,the ADL scores were increased(P<0.05),and the CSS(10.68±2.76)points in the observation group were lower than(15.69±2.73)points in the control group(t=8923,P<0.05),and the ADL(68.97± 10.28)points were higher than(56.44±11.49)points in the control group(t=6.529,P<0.05).Conclusion Ginkgo Leaf Extract and Dipyridamole Injection combined with alteplase intravenous thrombolysis in the treatment of elderly patients with ischemic stroke has a significant effect,can significantly enhance the daily life ability of patients and improve neurologi-cal function,with certain clinical value.

关键词

银杏达莫注射液/溶栓治疗/阿替普酶/老年缺血性卒中

Key words

Ginkgo Leaf Extract and Dipyridamole Injection/Thrombolytic Therapy/Alteplase/Ischemic Stroke in the Elderly

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出版年

2024
辽宁医学杂志
辽宁省医学会

辽宁医学杂志

影响因子:0.339
ISSN:1001-1722
参考文献量15
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