辽宁医学杂志2024,Vol.38Issue(1) :33-36.

肝动脉介入栓塞术对肝血管瘤患者并发症风险及炎症指标水平变化的影响

Influence of hepatic artery interventional embolization on the risk of complications and changes of inflammatory markers in patients with hepatic hemangioma

魏朝宁 曾启胜
辽宁医学杂志2024,Vol.38Issue(1) :33-36.

肝动脉介入栓塞术对肝血管瘤患者并发症风险及炎症指标水平变化的影响

Influence of hepatic artery interventional embolization on the risk of complications and changes of inflammatory markers in patients with hepatic hemangioma

魏朝宁 1曾启胜1
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作者信息

  • 1. 安阳市肿瘤医院(河南安阳 455000)
  • 折叠

摘要

目的 探究肝动脉介入栓塞术对肝血管瘤患者并发症风险及炎症指标水平变化的影响.方法 选择安阳市肿瘤医院介入科2019年4月至2021年5月期间接诊的92例肝血管瘤患者开展研究,随机抽签法分为对照组(n=46例)、观察组(n=46例),其中对照组进行常规开腹手术,观察组进行肝动脉介入栓塞术,比较总有效率、并发症及血清C-反应蛋白(CRP)、白细胞介素-4(IL-4)、白细胞介素-6(IL-6)等变化,采用生命质量测定量表(FACT-G)评价患者术后6个月期间的生存质量状况.结果 观察组总有效率91.3%较对照组71.4%高,差异有统计学意义(P<0.05);观察组术后3d血清CRP、IL-4水平增高幅度较对照组不明显,IL-6水平低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率较对照组低,差异有统计学意义(P<0.05);随访3个月,观察组FACT-G评分较对照组高,差异有统计学意义(P<0.05).结论 肝动脉介入栓塞术可调节患者炎症因子水平变化,控制机体炎症反应,延缓病情进展,减少并发症,优化生活质量.

Abstract

Objective To investigate the influence of hepatic artery interventional embolization on the risk of complica-tions and the level of inflammatory markers in patients with hepatic hemangioma.Methods 92 patients with hepatic he-mangioma admitted by the Interventional Department of Anyang Cancer Hospital from April 2019 to May 2021 were selected for the study.They were randomly divided into the control group(n=46 cases)and the observation group(n=46 cases).The control group underwent routine laparotomy,and the observation group underwent hepatic artery interventional emboliza-tion.The total efficiency,complications,serum C-reactive protein(CRP),interleukin-4(IL-4)Interleukin-6(IL-6)and other changes were measured by Quality of Life Inventory(FACT-G)during the 6 months after surgery.Results The total effec-tive rate of 91.3%in the observation group was higher than that of 71.4%in the control group(P<0.05);The level of se-rum CRP and IL-4 in the observation group was not significantly higher than that in the control group 3 days after operation,while the level of IL-6 was lower than that in the control group,with a statistically significant difference(P<0.05);The in-cidence of complications in the observation group was lower than that in the control group The FACT-G score in the observa-tion group was higher than that in the control group after 3 months of follow-up(P<0.05).Conclusion Hepatic artery in-terventional embolization can regulate the level of inflammatory factors in patients,control the inflammatory reaction of the body,delay the progress of the disease,reduce complications,and optimize the quality of life.

关键词

肝血管瘤/肝动脉介入栓塞术/并发症/炎症指标

Key words

Hepatic hemangioma/Hepatic artery interventional embolization/complication/Inflammatory indicators

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出版年

2024
辽宁医学杂志
辽宁省医学会

辽宁医学杂志

影响因子:0.339
ISSN:1001-1722
参考文献量15
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