摘要
目的 分析妊娠期高血压疾病患者围产儿不良结局与脐动脉血流的关系.方法 前瞻性选择医院2020年1月至2022年1月诊治的妊娠期高血压疾病患者70例,将其纳入病例组.另在同期选择体检健康的孕妇70例,将其纳入对照组.用彩色多普勒超声检查仪在患者妊娠晚期(胎儿出生前3d)监测脐动脉血流[脐动脉血流搏动指数(PI)、阻力指数(RI)、收缩压最大血流速度与舒张末期最大血流速度比值(S/D)].统计新生儿窒息、低出生体重及早产儿发生情况.使用Pearson进行相关性分析.结果 病例组PI、RI、S/D值均高于对照组(P＜0.05).病例组新生儿窒息、低出生体重、早产儿率高于对照组(P＜0.05).新生儿窒息、低出生体重、早产儿PI、RI、S/D值差异比较有统计学意义(P＜0.05).新生儿窒息、低出生体重、早产儿与脐动脉血流PI、RI、S/D指标均呈负相关(P＜0.05).结论 妊娠期高血压疾病患者容易发生围产儿不良结局,常见新生儿窒息、低出生体重、早产儿;脐动脉血流中PI、RI、S/D值可以作为预测妊娠期高血压疾病患者围产儿不良结局的指标.
Abstract
Objective To analyze the correlation between adverse perinatal outcomes and umbilical artery blood flow in patients with pregnancy-induced hypertension syndrome.Methods Seventy women with pregnancy-induced hypertension syndrome in our hospital from January 2020 to January 2022 were prospectively enrolled as case group,meantime,another 70 healthy healthy women were set as control group.Umbilical arterial blood flow parameters[pulsatility index(PI),resistance index(RI),systolic-diastolic ratio(S/D)]were monitored by color Doppler ultrasound in the third trimester of pregnancy(3d before fetal birth).The incidence rate of neonatal asphyxia,low birth weight and premature infants was recorded,then Pearson correlation analysis was performed.Results Case group had elevated PI,RI and S/D compared with control group(P＜0.05).Case group had increased rate of neonatal asphyxia,low birth weight and premature infants than control group(P＜0.05).PI,RI and S/D values varied among women with neonatal asphyxia,low birth weight and premature infants,with statistical difference(P＜0.05).The incidence rate of neonatal asphyxia,low birth weight and premature infants were negatively correlated with PI,RI and S/D(P＜0.05).Conclusion Patients with pregnancy-induced hypertension syn-drome suffer a high risk of adverse perinatal outcomes,such as neonatal asphyxia,low birth weight,and prematurity,while PI,RI,and S/D values in umbilical artery blood flow can be used as predictors of adverse perinatal outcomes in patients.
维普
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