甲状腺微小乳头状癌中央区淋巴结转移危险因素分析
Risk factors for central lymph node metastasis in papillary thyroid microcarcinoma
张蕊1
作者信息
- 1. 太康县人民医院(河南周口 461400)
- 折叠
摘要
目的 探究影响甲状腺微小乳头状癌(PTMC)中央区淋巴结转移的危险因素.方法 回顾性分析2019年4月到2021年4月我院收治的169例PTMC患者,按照是否发生中央区淋巴结转移分为转移组(n=48)和未转移组(n=121),收集患者临床资料,采用Logistic回归分析影响患者发生淋巴结转移的高危因素.结果 单因素分析显示,性别、肿瘤直径、临床分期、被膜侵犯、双侧甲状腺受累与PTMC患者发生中央区淋巴结转移有关(P＜0.05);多因素Logistic回归分析显示,肿瘤直径、临床分期、被膜侵犯、双侧甲状腺受累是影响PTMC患者发生中央区淋巴结转移的高危因素(P＜0.05).结论 PTMC患者的肿瘤直径≥5mm、临床分期cN1期、被膜侵犯、双侧甲状腺受累是发生中央区淋巴结转移的高危因素,临床可针对高危患者进行中央区淋巴结清除.
Abstract
Objective To explore the risk factors that affect central lymph node metastasis in papillary thyroid micro-carcinoma(PTMC).Methods A retrospective analysis was performed in 169 patients with PTMC admitted to our hospital from April 2019 to April 2021,and they were divided into metastatic group(n=48)and non-metastatic group(n=121)ac-cording to whether the central lymph node metastasis occurred with clinical data collected.Logistic regression analysis was conducted in high-risk factors that affect patients with lymph node metastasis.Results Univariate analysis showed that gen-der,tumor diameter,clinical stage,capsule invasion,bilateral thyroid involvement were associated with central lymph node metastasis in patients with PTMC(P＜0.05);multivariate logistic regression analysis showed that tumor diameter,clinical stage,capsule invasion and bilateral thyroid involvement were high-risk factors for central lymph node metastasis in patients with PTMC(P＜0.05).Conclusion PTMC patients with tumor diameter ≥5 mm,clinical stage in cN1,capsule invasion and bilateral thyroid involvement are high-risk factors for central lymph node metastasis.Central lymph node removal can be performed in high-risk patients.
关键词
甲状腺微小乳头状癌/淋巴结转移/危险因素Key words
Papillary thyroid microcarcinoma/Lymph node metastasis/Risk factors引用本文复制引用
出版年
2024
NETL
NSTL
万方数据