Peptic ulcers are mainly chronic ulcers that occur in the stomach and duodenum,with clinical symptoms such as upper and middle abdominal pain and acid reflux,with periodic and rhythmic episodes.The proton pump inhibitor lanso-prazole acts on the H+-K+-ATPase system and is converted into hyposulfonic acid and hyposulfhydryl derivatives through the mural cell membrane,which can adjust the acid-base value in the patient's stomach and inhibit the activity of Helicobacter pylori,with high drug safety,and can be used as the drug of choice in the clinical treatment of peptic ulcer.Therefore,the arti-cle intends to review the mechanism of action of lansoprazole,its therapeutic effect on peptic ulcer,and the latest research pro-gress of combining with other drugs for the treatment of peptic ulcer,in order to provide reference for clinical use.
维普
万方数据