Distribution of Pathogens Causing Postoperative Infections in Women with Cesarean Section and Analysis of Optimal Cutoff Threshold of CRP for Prediction of Incision Infection
Distribution of Pathogens Causing Postoperative Infections in Women with Cesarean Section and Analysis of Optimal Cutoff Threshold of CRP for Prediction of Incision Infection
Objective To analyze the distribution of pathogens causing postoperative infections in women with cesarean section,and to study the optimal cutoff threshold of C-reactive protein(CRP)for prediction of infection.Methods A sample of 965 women underwent cesarean section in our hospital from April 2021 to April 2022 were enrolled,and classified into two groups according to the presence or absence of postoperative infection,infection group(n=35)and control group(n=930).The pathogen profile of incisional secretions was detected.CRP levels before,24h,48h,72h and 96h after delivery were compared,then the predictive value of CRP at different time points for maternal postoperative incision infection was e-valuated.Results A total of 42 strains of pathogens were isolated from 35 infected cases,with 29 strains of Gram-negative bacteria(69％),mainly Escherichia coli and Gardnerella vaginalis,accounting for 48.27％and 31.03％respectively.There were 11 strains of Gram-positive bacteria,accounting for 26.19％,mainly Hemolytic streptococcus and Enterococcus faeca-lis,accounting for 63.63％and 27.27％respectively.There were 2 strains of fungi,accounting for 4.76％.CRP levels in control group at 72h and 96h after delivery were significantly lower than those at 24h after delivery(P＜0.05).CRP levels in control group at 72h and 96h after delivery were significantly higher than those before,24h and 96h after delivery,with statistical difference(all P＜0.05).CRP levels at 24h,72h and 96h after delivery were significantly elevated in infection group compared with contorl group at corresponding time points(all P＜0.05).Among the values at different time points,CRP at 48h after delivery had the highest predictive value for postpartum infection(P＜0.05).Conclusion Gram-negative bacteria are the main pathogens causing postpartum cesarean section infection,and CRP at 48h after delivery has high effi-cacy for prediction of incision infection.
维普
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