Objective To analyze the effect of ADOPT nursing in patients with metabolic syndrome(MS).Methods 120 pa-tients with MS from June 2020 to June 2022 were divided into control group(n=60)and observation group(n=60)by prospective study method and random number table method.The control group was treated with routine clinical intervention,and the observa-tion group was treated with ADOPT nursing intervention.The compliance behavior,medication compliance,self-management effica-cy score and the level of MS-related indicators of the two groups were compared 1 day before intervention and 1 day after inter-vention.Results Compared with the control group,the observation group had better compliance behaviors and medication compliance after intervention;After intervention,the scores of self-management efficacy in the observation group increased;After the intervention,the levels of all MS related indicators in the observation group decreased significantly(P<0.05).Conclusion ADOPT nursing can improve the compliance behavior and medication compliance of patients with metabolic syndrome and improve the self-management efficiency,which can help promote the stability of MS patients.